pH-Dependent silica nanoparticle dissolution and cargo release
نویسندگان
چکیده
منابع مشابه
SUPPORTING INFORMATION Nanoparticle-based pseudo hapten for target-responsive cargo release for magnetic mesoporous silica nanocontainer
EXPERIMENTAL PROCESS ......................................................................................................................................................S2 1. Materials and Reagents ....................................................................................................................................................S2 2. Apparatus ....................................
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The vacuolar proton-translocating ATPase (V-ATPase) plays a major role in organelle acidification and works together with other ion transporters to maintain pH homeostasis in eukaryotic cells. We analyzed a requirement for V-ATPase activity in protein trafficking in the yeast secretory pathway. Deficiency of V-ATPase activity caused by subunit deletion or glucose deprivation results in missorti...
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Figure 2 Experiment B: dissolution of Salofalk 1.5 g granules (batch no. 10F18833L) and Mezavant 1200 mg (batch no VB032) at sequential pH 1.0, 6.0, and 6.8 (n=6). We have read with interest the abstract presented at the last ECCO Congress by Tenjarla & Abinusawa1. While we agree with the authors' final statement that ‘consideration of the potential release profiles [of 5-ASA] may be a useful t...
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Peroxidase mimetic catalytic atom transfer radical polymerization (ATRP) was first used to install tertiary amine-functionalized polymer brushes on the surface of mesoporous silica nanoparticles (MSNs) in a facile and highly efficient manner. Poly(N,N-dimethylaminoethyl methacrylate) (PDMAEMA) brushes-grafted MSNs were fabricated by biocompatible deuteroheminβ-Ala-His-Thr-Val-Glu-Lys (DhHP-6)-c...
متن کاملpH-Controllable drug release using hydrogel encapsulated mesoporous silica.
Amine-functionalized mesoporous SBA-15 silica loaded with bovine serum albumin (BSA) has been successfully encapsulated with a thin layer coating of poly(acrylic acid) PAA, with the entrapped BSA being released from the PAA-encapsulated SBA-15 at the higher pH value of 7.4 rather than at the lower pH value of 1.2. This novel drug delivery system has a potential application in the release of pro...
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ژورنال
عنوان ژورنال: Colloids and Surfaces B: Biointerfaces
سال: 2018
ISSN: 0927-7765
DOI: 10.1016/j.colsurfb.2018.04.064